Elaine Jolly, Andrew Fry, Afzal Chaudhry

What should we do if we don’t anticipate any difference?
Sometimes we do not wish to detect a difference, because we do not think that there will be one. We might have a trial where we expect or hope to show that two treatments are similar in their effects on the primary outcome. The better treatment would then be decided on the basis of secondary outcomes, such as side effects or cost.

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3 Responses to Elaine Jolly, Andrew Fry, Afzal Chaudhry

  1. shinichi says:

    Training in Medicine

    edited by Elaine Jolly, Andrew Fry, Afzal Chaudhry

    Chapter 20
    Epidemiology and evidence-based medicine

    (p. 851)

  2. shinichi says:

    “Expect” has the idea that it is going to happen, or is very likely, but has no emotion attached.

    “Hope” is a bit less definite than “Expect”.

    “Wish” is a bit more general than “Expect”. It involves emotion.

    “Want” is a desire, like “Wish”.

    “Anticipate” is very similar to “Expect”, but has an implication of emotion.


  3. shinichi says:


    Medicine って、いつも evidence-based で、

    でもそのわりには、anticipate だし wish だし expect だし hope だし、

    なんなんだ? この感じ。

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